Computational prediction of vaccine potential epitopes and 3-dimensional structure of XAGE-1b for non-small cell lung cancer immunotherapy
Background: XAGE-1b is shown to be overexpressed in lung adenocarcinoma and to be a strong immunogenic antigen among non-small cell lung cancer (NSCLC) patients.However, 3D structure of XAGE-1b is not available and its confirmation has not been solved yet.Methods: Multiple sequence alignment was run to select the most reliable templates.Homology mo